منابع مشابه
Salt sensitivity in blacks. Salt intake and natriuretic substances.
Accumulating evidence suggests that hypertension in blacks is manifested in part by impaired renal excretion of salt. Consequently, this study was performed to determine if hypertensive and normotensive black subjects differ in their ability to generate known natriuretic substances. Fourteen normotensive and 11 hypertensive blacks were maintained on constant metabolic diets containing either 40...
متن کاملSodium-selective salt sensitivity: its occurrence in blacks.
We tested the hypothesis that the Na(+) component of dietary NaCl can have a pressor effect apart from its capacity to complement the extracellular osmotic activity of Cl(-) and, thus, expand plasma volume. We studied 35 mostly normotensive blacks who ingested a low-NaCl diet, 30 mmol/d, for 3 weeks, in the first and third of which Na(+) was loaded orally with either NaHCO(3) or NaCl, in random...
متن کاملSalt-Sensitivity Salt Sensitivity in Blacks Evidence That the Initial Pressor Effect of NaCl Involves Inhibition of Vasodilatation by Asymmetrical Dimethylarginine
In healthy, mostly normotensive blacks, 19 salt-sensitive (SS) and 18 salt-resistant (SR), we tested the hypothesis that, in SS subjects, dietary NaCl loading induces its initial pressor effect by inducing a normal increase of cardiac output, while failing to induce a normal pressor-offsetting vasodilatation, consequent to its inhibition by asymmetrical dimethylarginine that is abnormally incre...
متن کاملWhy is salt-sensitive hypertension so common in blacks?
Americans to develop end-stage renal disease. The Introduction mechanisms responsible for these pathophysiological changes remain unexplained. Hypertension is more prevalent among blacks and it carries a worse cardiovascular and renal prognosis than in whites. Data from the United States Renal Data System (USRDS) show that over the past decade, Hypothesis the incidence of ESRD has steadily incr...
متن کاملSalt sensitivity in blacks: evidence that the initial pressor effect of NaCl involves inhibition of vasodilatation by asymmetrical dimethylarginine.
In healthy, mostly normotensive blacks, 19 salt-sensitive (SS) and 18 salt-resistant (SR), we tested the hypothesis that, in SS subjects, dietary NaCl loading induces its initial pressor effect by inducing a normal increase of cardiac output, while failing to induce a normal pressor-offsetting vasodilatation, consequent to its inhibition by asymmetrical dimethylarginine that is abnormally incre...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2011
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.111.170175